Visualizing Ligand Binding to a GPCR In Vivo Using NanoBRET

The therapeutic action of a drug depends on its ability to engage with its molecular target in vivo. However, current drug discovery strategies quantify drug levels within organs rather than determining the binding of drugs directly to their specific molecular targets in vivo. This is a particular p...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:iScience
Päätekijät: Alcobia, Diana C., Ziegler, Alexandra I., Kondrashov, Alexander, Comeo, Eleonora, Mistry, Sarah, Kellam, Barrie, Chang, Aeson, Woolard, Jeanette, Hill, Stephen J., Sloan, Erica K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6137713/
https://ncbi.nlm.nih.gov/pubmed/30240618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.08.006
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia