An Integrated Approach toward NanoBRET Tracers for Analysis of GPCR Ligand Engagement

Gaining insight into the pharmacology of ligand engagement with G-protein coupled receptors (GPCRs) under biologically relevant conditions is vital to both drug discovery and basic research. NanoLuc-based bioluminescence resonance energy transfer (NanoBRET) monitoring competitive binding between flu...

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Vydáno v:Molecules
Hlavní autoři: Killoran, Michael P., Levin, Sergiy, Boursier, Michelle E., Zimmerman, Kristopher, Hurst, Robin, Hall, Mary P., Machleidt, Thomas, Kirkland, Thomas A., Friedman Ohana, Rachel
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8151276/
https://ncbi.nlm.nih.gov/pubmed/34065854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26102857
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