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Visualizing Ligand Binding to a GPCR In Vivo Using NanoBRET
The therapeutic action of a drug depends on its ability to engage with its molecular target in vivo. However, current drug discovery strategies quantify drug levels within organs rather than determining the binding of drugs directly to their specific molecular targets in vivo. This is a particular p...
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| 發表在: | iScience |
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| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6137713/ https://ncbi.nlm.nih.gov/pubmed/30240618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.08.006 |
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