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N(6)-methyladenine DNA Modification in Glioblastoma

Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. While the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognized, the functions of other non-canonical DNA modifications remain obsure. Here, we report the identification of n...

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Publicado en:Cell
Main Authors: Xie, Qi, Wu, Tao P., Gimple, Ryan C., Li, Zheng, Prager, Briana C., Wu, Qiulian, Yu, Yang, Wang, Pengcheng, Wang, Yinsheng, Gorkin, David U., Zhang, Cheng, Dowiak, Alexis V., Lin, Kaixuan, Zeng, Chun, Sui, Yinghui, Kim, Leo J. Y., Miller, Tyler E., Jiang, Li, Lee-Poturalski, Christine, Huang, Zhi, Fang, Xiaoguang, Zhai, Kui, Mack, Stephen C., Sander, Maike, Bao, Shideng, Kerstetter-Fogle, Amber E., Sloan, Andrew E., Xiao, Andrew Z., Rich, Jeremy N.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433469/
https://ncbi.nlm.nih.gov/pubmed/30392959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.10.006
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