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Chemical and biochemical strategies to explore the substrate recognition of O-GlcNAc cycling enzymes
The O-linked N-acetylglucosamine (O-GlcNAc) modification is an essential component in cell regulation. A single pair of human enzymes conducts this modification dynamically on a broad variety of proteins: O-GlcNAc transferase (OGT) adds the GlcNAc residue and O-GlcNAcase (OGA) hydrolyzes it. This mo...
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| Publicado en: | Chembiochem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6433133/ https://ncbi.nlm.nih.gov/pubmed/30199580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800481 |
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