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Chemical and biochemical strategies to explore the substrate recognition of O-GlcNAc cycling enzymes

The O-linked N-acetylglucosamine (O-GlcNAc) modification is an essential component in cell regulation. A single pair of human enzymes conducts this modification dynamically on a broad variety of proteins: O-GlcNAc transferase (OGT) adds the GlcNAc residue and O-GlcNAcase (OGA) hydrolyzes it. This mo...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Hu, Chia-Wei, Worth, Matthew, Li, Hao, Jiang, Jiaoyang
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433133/
https://ncbi.nlm.nih.gov/pubmed/30199580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800481
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