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Structural characterization of the O-GlcNAc cycling enzymes: insights into substrate recognition and catalytic mechanisms
Dysregulation of nuclear and cytoplasmic O-linked β-N-acetylglucosamine (O-GlcNAc) cycling is implicated in a range of diseases including diabetes and cancer. This modification maintains cellular homeostasis by regulating several biological processes, such as cell signaling. This highly regulated cy...
Gorde:
| Argitaratua izan da: | Curr Opin Struct Biol |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6656603/ https://ncbi.nlm.nih.gov/pubmed/30708324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2018.12.003 |
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