Loading...

Iterative Design of Emetine-Based Prodrug Targeting Fibroblast Activation Protein (FAP) and Dipeptidyl Peptidase IV DPPIV Using a Tandem Enzymatic Activation Strategy

BACKGROUND. There is an urgent need to develop new agents for treating metastatic prostate cancer to overcome multiple drug resistance to the current standard targeted cancer therapy. Emetine is a highly cytotoxic natural product protein synthesis inhibitor, which is toxic to all cell types. Its cyt...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Prostate
Main Authors: Akinboye, Emmanuel S., Brennen, W. Nathaniel, Rosen, D. Marc, Bakare, Oladapo, Denmeade, Samuel R.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6432629/
https://ncbi.nlm.nih.gov/pubmed/26835873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23162
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!