DESIGN, SYNTHESIS AND CYTOTOXICITY STUDIES OF DITHIOCARBAMATE ESTER DERIVATIVES OF EMETINE IN PROSTATE CANCER CELL LINES.

A small library of emetine dithiocarbamate ester derivatives were synthesized in 25–86% yield via derivatization of the N2’- position of emetine. Anticancer evaluation of these compounds in androgen receptor positive LNCaP and androgen receptor negative PC3 and DU145 prostate cancer cell lines revea...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Akinboye, Emmanuel S., Bamji, Zebalda D., Kwabi-Addo, Bernard, Ejeh, David, Copeland, Robert L., Denmeade, Samuel R, Bakare, Oladapo
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481605/
https://ncbi.nlm.nih.gov/pubmed/26187015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.06.072
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