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DESIGN, SYNTHESIS AND CYTOTOXICITY STUDIES OF DITHIOCARBAMATE ESTER DERIVATIVES OF EMETINE IN PROSTATE CANCER CELL LINES.
A small library of emetine dithiocarbamate ester derivatives were synthesized in 25–86% yield via derivatization of the N2’- position of emetine. Anticancer evaluation of these compounds in androgen receptor positive LNCaP and androgen receptor negative PC3 and DU145 prostate cancer cell lines revea...
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| Pubblicato in: | Bioorg Med Chem |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6481605/ https://ncbi.nlm.nih.gov/pubmed/26187015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.06.072 |
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