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Longer Heating Duration Increases Localized Doxorubicin Deposition and Therapeutic Index in Vx2 Tumors using MR-HIFU Mild Hyperthermia and Thermosensitive Liposomal Doxorubicin
Thermosensitive liposomal doxorubicin (LTSL-Dox) combined with mild hyperthermia enhances the localized delivery of doxorubicin (Dox) within a heated region. The optimal heating duration and the impact of extended heating on systemic drug distribution is unknown. Here we evaluated local and systemic...
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| Publicado no: | Int J Hyperthermia |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6430695/ https://ncbi.nlm.nih.gov/pubmed/30541350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/02656736.2018.1550815 |
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