Longer Heating Duration Increases Localized Doxorubicin Deposition and Therapeutic Index in Vx2 Tumors using MR-HIFU Mild Hyperthermia and Thermosensitive Liposomal Doxorubicin

Thermosensitive liposomal doxorubicin (LTSL-Dox) combined with mild hyperthermia enhances the localized delivery of doxorubicin (Dox) within a heated region. The optimal heating duration and the impact of extended heating on systemic drug distribution is unknown. Here we evaluated local and systemic...

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Bibliografiset tiedot
Julkaisussa:Int J Hyperthermia
Päätekijät: Bing, Chenchen, Patel, Pratik, Staruch, Robert M., Shaikh, Sumbul, Nofiele, Joris, Wodzak Staruch, Michelle, Szczepanski, Debra, Williams, Noelle S., Laetsch, Theodore, Chopra, Rajiv
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430695/
https://ncbi.nlm.nih.gov/pubmed/30541350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/02656736.2018.1550815
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