Načítá se...

Discovery of New CDK8/CycC ligands with a Novel Virtual Screening Tool

Selective inhibition of Cyclin-dependent kinase 8 and cyclin C (CDK8/CycC) has been suggested as a promising strategy for reducing mitogenic signals in cancer cells with reduced toxic effects on normal cells. We developed a novel virtual screening protocol for drug development and applied it to disc...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:ChemMedChem
Hlavní autoři: Chen, Wei, Ren, Xiaodong, Chang, Chia-en A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6428209/
https://ncbi.nlm.nih.gov/pubmed/30403831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201800559
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!