mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC)

In non-alcoholic fatty liver disease (NAFLD) and insulin resistance, hepatic de novo lipogenesis is often elevated, but the underlying mechanisms remain poorly understood. Recently, we show that CDK8 functions to suppress de novo lipogenesis. Here, we identify the mammalian target of rapamycin compl...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Feng, Daorong, Youn, Dou Yeon, Zhao, Xiaoping, Gao, Yanguang, Quinn, William J., Xiaoli, Alus M., Sun, Yan, Birnbaum, Morris J., Pessin, Jeffrey E., Yang, Fajun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456374/
https://ncbi.nlm.nih.gov/pubmed/26042770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126240
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak