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Structure–kinetic relationship study of CDK8/CycC specific compounds

In contrast with the very well explored concept of structure–activity relationship, similar studies are missing for the dependency between binding kinetics and compound structure of a protein ligand complex, the structure–kinetic relationship. Here, we present a structure–kinetic relationship study...

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Détails bibliographiques
Auteurs principaux: Schneider, Elisabeth V., Böttcher, Jark, Huber, Robert, Maskos, Klaus, Neumann, Lars
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657768/
https://ncbi.nlm.nih.gov/pubmed/23630251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1305378110
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