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Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion

The deregulation of metabolism is a hallmark of aging. As such, changes in the expression of metabolic genes and the profiles of amino acid levels are features associated with aging animals. We previously reported that the levels of most amino acids decline with age in Caenorhabditis elegans (C. ele...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Liu, Yasmine J., Janssens, Georges E., McIntyre, Rebecca L., Molenaars, Marte, Kamble, Rashmi, Gao, Arwen W., Jongejan, Aldo, van Weeghel, Michel, MacInnes, Alyson W., Houtkooper, Riekelt H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6424468/
https://ncbi.nlm.nih.gov/pubmed/30845140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007633
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