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Mitochondrial cross-compartmental signalling to maintain proteostasis and longevity
Lifespan in eukaryotic species can be prolonged by shifting from cellular states favouring growth to those favouring maintenance and stress resistance. For instance, perturbations in mitochondrial oxidative phosphorylation (OXPHOS) can shift cells into this latter state and extend lifespan. Because...
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| Publicado no: | Philos Trans R Soc Lond B Biol Sci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7209959/ https://ncbi.nlm.nih.gov/pubmed/32362258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2019.0414 |
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