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Mitochondrial cross-compartmental signalling to maintain proteostasis and longevity

Lifespan in eukaryotic species can be prolonged by shifting from cellular states favouring growth to those favouring maintenance and stress resistance. For instance, perturbations in mitochondrial oxidative phosphorylation (OXPHOS) can shift cells into this latter state and extend lifespan. Because...

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Bibliografski detalji
Izdano u:Philos Trans R Soc Lond B Biol Sci
Glavni autori: Molenaars, Marte, Daniels, Eileen G., Meurs, Amber, Janssens, Georges E., Houtkooper, Riekelt H.
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7209959/
https://ncbi.nlm.nih.gov/pubmed/32362258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2019.0414
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