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UFL1 promotes histone H4 ufmylation and ATM activation

The ataxia-telangiectasia mutated (ATM) kinase, an upstream kinase of the DNA damage response (DDR), is rapidly activated following DNA damage, and phosphorylates its downstream targets to launch DDR signaling. However, the mechanism of ATM activation is still not completely understood. Here we repo...

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書目詳細資料
發表在:Nat Commun
Main Authors: Qin, Bo, Yu, Jia, Nowsheen, Somaira, Wang, Minghui, Tu, Xinyi, Liu, Tongzheng, Li, Honglin, Wang, Liewei, Lou, Zhenkun
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423285/
https://ncbi.nlm.nih.gov/pubmed/30886146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09175-0
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