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Regulation of serine/threonine kinase Akt Activation by NAD(+)-dependent deacetylase SIRT7
The Akt pathway is a central regulator that promotes cell survival in response to extracellular signals. Depletion of SIRT7, a NAD(+)-dependent deacetylase which is the least studied sirtuin, is known to significantly increase Akt activity in mice through unknown mechanisms. In this study, we demons...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5298804/ https://ncbi.nlm.nih.gov/pubmed/28147277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.01.009 |
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