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UFL1 promotes histone H4 ufmylation and ATM activation

The ataxia-telangiectasia mutated (ATM) kinase, an upstream kinase of the DNA damage response (DDR), is rapidly activated following DNA damage, and phosphorylates its downstream targets to launch DDR signaling. However, the mechanism of ATM activation is still not completely understood. Here we repo...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Qin, Bo, Yu, Jia, Nowsheen, Somaira, Wang, Minghui, Tu, Xinyi, Liu, Tongzheng, Li, Honglin, Wang, Liewei, Lou, Zhenkun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6423285/
https://ncbi.nlm.nih.gov/pubmed/30886146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09175-0
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