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Mutating for Good: DNA Damage Responses During Somatic Hypermutation
Somatic hypermutation (SHM) of immunoglobulin (Ig) genes plays a key role in antibody mediated immunity. SHM in B cells provides the molecular basis for affinity maturation of antibodies. In this way SHM is key in optimizing antibody dependent immune responses. SHM is initiated by targeting the Acti...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6423074/ https://ncbi.nlm.nih.gov/pubmed/30915081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00438 |
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