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DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy

The DNA damage response network guards the stability of the genome from a plethora of exogenous and endogenous insults. An essential feature of the DNA damage response network is its capacity to tolerate DNA damage and structural impediments during DNA synthesis. This capacity, referred to as DNA da...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Pilzecker, Bas, Buoninfante, Olimpia Alessandra, Jacobs, Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698745/
https://ncbi.nlm.nih.gov/pubmed/31251805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz531
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