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DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy

The DNA damage response network guards the stability of the genome from a plethora of exogenous and endogenous insults. An essential feature of the DNA damage response network is its capacity to tolerate DNA damage and structural impediments during DNA synthesis. This capacity, referred to as DNA da...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Pilzecker, Bas, Buoninfante, Olimpia Alessandra, Jacobs, Heinz
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6698745/
https://ncbi.nlm.nih.gov/pubmed/31251805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz531
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