DNA damage tolerance in hematopoietic stem and progenitor cells in mice

DNA damage tolerance (DDT) enables bypassing of DNA lesions during replication, thereby preventing fork stalling, replication stress, and secondary DNA damage related to fork stalling. Three modes of DDT have been documented: translesion synthesis (TLS), template switching (TS), and repriming. TLS a...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Pilzecker, Bas, Buoninfante, Olimpia Alessandra, van den Berk, Paul, Lancini, Cesare, Song, Ji-Ying, Citterio, Elisabetta, Jacobs, Heinz
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
Témata:
PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5565453/
https://ncbi.nlm.nih.gov/pubmed/28761001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1706508114
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky