Statins affect human glioblastoma and other cancers through TGF-β inhibition

The cholesterol-lowering statins have known anti-cancer effects, but the mechanisms and how to utilize statins in oncology have been unclear. We noted in the CellMiner database that statin activity against cancer lines correlated with higher expression of TGF-β target genes such as SERPINE1 and ZYX....

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Oncotarget
Main Authors: Xiao, Aizhen, Brenneman, Breanna, Floyd, Desiree, Comeau, Laurey, Spurio, Kelsey, Olmez, Inan, Lee, Jeongwu, Nakano, Ichiro, Godlewski, Jakub, Bronisz, Agnieszka, Kagaya, Noritaka, Shin-ya, Kazuo, Purow, Benjamin
פורמט: Artigo
שפה:Inglês
יצא לאור: Impact Journals LLC 2019
נושאים:
Research Paper
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422202/
https://ncbi.nlm.nih.gov/pubmed/30899443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26733
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