Statins affect human glioblastoma and other cancers through TGF-β inhibition

The cholesterol-lowering statins have known anti-cancer effects, but the mechanisms and how to utilize statins in oncology have been unclear. We noted in the CellMiner database that statin activity against cancer lines correlated with higher expression of TGF-β target genes such as SERPINE1 and ZYX....

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Xiao, Aizhen, Brenneman, Breanna, Floyd, Desiree, Comeau, Laurey, Spurio, Kelsey, Olmez, Inan, Lee, Jeongwu, Nakano, Ichiro, Godlewski, Jakub, Bronisz, Agnieszka, Kagaya, Noritaka, Shin-ya, Kazuo, Purow, Benjamin
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2019
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422202/
https://ncbi.nlm.nih.gov/pubmed/30899443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26733
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