CDK4/6 inhibition is more active against the glioblastoma proneural subtype

Glioblastoma (GBM) is the most common and lethal brain tumor. Gene expression profiling has classified GBM into distinct subtypes, including proneural, mesenchymal, and classical, and identifying therapeutic vulnerabilities of these subtypes is an extremely high priority. We leveraged The Cancer Gen...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Li, Ming, Xiao, Aizhen, Floyd, Desiree, Olmez, Inan, Lee, Jeongwu, Godlewski, Jakub, Bronisz, Agnieszka, Bhat, Krishna P.L., Sulman, Erik P., Nakano, Ichiro, Purow, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589661/
https://ncbi.nlm.nih.gov/pubmed/28903422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19429
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