CDK4/6 inhibition is more active against the glioblastoma proneural subtype

Glioblastoma (GBM) is the most common and lethal brain tumor. Gene expression profiling has classified GBM into distinct subtypes, including proneural, mesenchymal, and classical, and identifying therapeutic vulnerabilities of these subtypes is an extremely high priority. We leveraged The Cancer Gen...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Li, Ming, Xiao, Aizhen, Floyd, Desiree, Olmez, Inan, Lee, Jeongwu, Godlewski, Jakub, Bronisz, Agnieszka, Bhat, Krishna P.L., Sulman, Erik P., Nakano, Ichiro, Purow, Benjamin
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589661/
https://ncbi.nlm.nih.gov/pubmed/28903422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19429
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