Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha

BACKGROUND: The mesenchymal phenotype in glioblastoma (GBM) and other cancers drives aggressiveness and treatment resistance, leading to therapeutic failure and recurrence of disease. Currently, there is no successful treatment option available against the mesenchymal phenotype. METHODS: We classifi...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Olmez, Inan, Love, Shawn, Xiao, Aizhen, Manigat, Laryssa, Randolph, Peyton, McKenna, Brian D, Neal, Brian P, Boroda, Salome, Li, Ming, Brenneman, Breanna, Abounader, Roger, Floyd, Desiree, Lee, Jeongwu, Nakano, Ichiro, Godlewski, Jakub, Bronisz, Agnieszka, Sulman, Erik P, Mayo, Marty, Gioeli, Daniel, Weber, Michael, Harris, Thurl E, Purow, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777487/
https://ncbi.nlm.nih.gov/pubmed/29048560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox119
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