Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha

BACKGROUND: The mesenchymal phenotype in glioblastoma (GBM) and other cancers drives aggressiveness and treatment resistance, leading to therapeutic failure and recurrence of disease. Currently, there is no successful treatment option available against the mesenchymal phenotype. METHODS: We classifi...

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Библиографические подробности
Опубликовано в: :Neuro Oncol
Главные авторы: Olmez, Inan, Love, Shawn, Xiao, Aizhen, Manigat, Laryssa, Randolph, Peyton, McKenna, Brian D, Neal, Brian P, Boroda, Salome, Li, Ming, Brenneman, Breanna, Abounader, Roger, Floyd, Desiree, Lee, Jeongwu, Nakano, Ichiro, Godlewski, Jakub, Bronisz, Agnieszka, Sulman, Erik P, Mayo, Marty, Gioeli, Daniel, Weber, Michael, Harris, Thurl E, Purow, Benjamin
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
Предметы:
Basic and Translational Investigations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777487/
https://ncbi.nlm.nih.gov/pubmed/29048560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox119
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