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Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha

BACKGROUND: The mesenchymal phenotype in glioblastoma (GBM) and other cancers drives aggressiveness and treatment resistance, leading to therapeutic failure and recurrence of disease. Currently, there is no successful treatment option available against the mesenchymal phenotype. METHODS: We classifi...

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Bibliografski detalji
Izdano u:Neuro Oncol
Glavni autori: Olmez, Inan, Love, Shawn, Xiao, Aizhen, Manigat, Laryssa, Randolph, Peyton, McKenna, Brian D, Neal, Brian P, Boroda, Salome, Li, Ming, Brenneman, Breanna, Abounader, Roger, Floyd, Desiree, Lee, Jeongwu, Nakano, Ichiro, Godlewski, Jakub, Bronisz, Agnieszka, Sulman, Erik P, Mayo, Marty, Gioeli, Daniel, Weber, Michael, Harris, Thurl E, Purow, Benjamin
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777487/
https://ncbi.nlm.nih.gov/pubmed/29048560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox119
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