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Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha

BACKGROUND: The mesenchymal phenotype in glioblastoma (GBM) and other cancers drives aggressiveness and treatment resistance, leading to therapeutic failure and recurrence of disease. Currently, there is no successful treatment option available against the mesenchymal phenotype. METHODS: We classifi...

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Publicat a:Neuro Oncol
Autors principals: Olmez, Inan, Love, Shawn, Xiao, Aizhen, Manigat, Laryssa, Randolph, Peyton, McKenna, Brian D, Neal, Brian P, Boroda, Salome, Li, Ming, Brenneman, Breanna, Abounader, Roger, Floyd, Desiree, Lee, Jeongwu, Nakano, Ichiro, Godlewski, Jakub, Bronisz, Agnieszka, Sulman, Erik P, Mayo, Marty, Gioeli, Daniel, Weber, Michael, Harris, Thurl E, Purow, Benjamin
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5777487/
https://ncbi.nlm.nih.gov/pubmed/29048560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox119
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