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IMMU-51. ASSESSING AND AUGMENTING THE IMMUNE RESPONSE TO GLIOBLASTOMA USING REPURPOSED PHARMACEUTICALS

In order to improve the therapeutic responses to immunotherapies in glioblastoma patients, a known pharmaceutical, ritanserin, was repurposed to augment cytotoxic T cell responses and suppress tumor growth. Ritanserin is able to inhibit the activity of diacylglycerol kinase alpha (DGKA), which conve...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Brenneman, Breanna, Floyd, Desiree, Xiao, Aizhen, Malyakvo, Alisa, Harris, Tajie, Purow, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692415/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.509
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