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Linking Signaling and Selection in the Germinal Center

Germinal centers are sites of sites of rapid B cell proliferation in response to certain types of immunization. They arise in about one week and can persist for several months. In GCs, B cells differentiate in a unique way and begin to undergo somatic mutation of the Ig V regions at a high rate. GC...

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Bibliographic Details
Published in:Immunol Rev
Main Authors: Shlomchik, Mark J., Luo, Wei, Weisel, Florian
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422174/
https://ncbi.nlm.nih.gov/pubmed/30874353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12744
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