The AKT kinase signaling network is rewired by PTEN to control proximal BCR signaling in germinal center B cells

Compared to naïve B cells (NBCs), both B cell antigen receptor (BCR) and CD40 signaling are rewired in germinal center (GC) B cells (GCBCs) to optimize selection for high-affinity B cells. The mechanism for BCR reprogramming in GCBCs remains unknown. We describe a GC-specific, AKT kinase-driven nega...

全面介紹

Na minha lista:
書目詳細資料
發表在:Nat Immunol
Main Authors: Luo, Wei, Hawse, William, Conter, Laura, Trivedi, Nikita, Weisel, Florian, Wikenheiser, Daniel, Cattley, Richard T., Shlomchik, Mark J.
格式: Artigo
語言:Inglês
出版: 2019
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724213/
https://ncbi.nlm.nih.gov/pubmed/31011187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0376-3
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍