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Pten controls B‐cell responsiveness and germinal center reaction by regulating the expression of IgD BCR

In contrast to other B‐cell antigen receptor (BCR) classes, the function of IgD BCR on mature B cells remains largely elusive as mature B cells co‐express IgM, which is sufficient for development, survival, and activation of B cells. Here, we show that IgD expression is regulated by the forkhead box...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Setz, Corinna S, Khadour, Ahmad, Renna, Valerio, Iype, Joseena, Gentner, Eva, He, Xiaocui, Datta, Moumita, Young, Marc, Nitschke, Lars, Wienands, Jürgen, Maity, Palash C, Reth, Michael, Jumaa, Hassan
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545559/
https://ncbi.nlm.nih.gov/pubmed/31015337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100249
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