Pten controls B‐cell responsiveness and germinal center reaction by regulating the expression of IgD BCR

In contrast to other B‐cell antigen receptor (BCR) classes, the function of IgD BCR on mature B cells remains largely elusive as mature B cells co‐express IgM, which is sufficient for development, survival, and activation of B cells. Here, we show that IgD expression is regulated by the forkhead box...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Setz, Corinna S, Khadour, Ahmad, Renna, Valerio, Iype, Joseena, Gentner, Eva, He, Xiaocui, Datta, Moumita, Young, Marc, Nitschke, Lars, Wienands, Jürgen, Maity, Palash C, Reth, Michael, Jumaa, Hassan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6545559/
https://ncbi.nlm.nih.gov/pubmed/31015337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018100249
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