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Continuous signaling of CD79b and CD19 is required for the fitness of Burkitt lymphoma B cells

Expression of the B‐cell antigen receptor (BCR) is essential not only for the development but also for the maintenance of mature B cells. Similarly, many B‐cell lymphomas, including Burkitt lymphoma (BL), require continuous BCR signaling for their tumor growth. This growth is driven by immunorecepto...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: He, Xiaocui, Kläsener, Kathrin, Iype, Joseena M, Becker, Martin, Maity, Palash C, Cavallari, Marco, Nielsen, Peter J, Yang, Jianying, Reth, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983214/
https://ncbi.nlm.nih.gov/pubmed/29669863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797980
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