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B cell activation involves nanoscale receptor reorganizations and inside-out signaling by Syk
Binding of antigen to the B cell antigen receptor (BCR) initiates a multitude of events resulting in B cell activation. How the BCR becomes signaling-competent upon antigen binding is still a matter of controversy. Using a high-resolution proximity ligation assay (PLA) to monitor the conformation of...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4067077/ https://ncbi.nlm.nih.gov/pubmed/24963139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02069 |
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