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The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development
Upon B-cell antigen receptor (BCR) activation, the protein tyrosine kinase Syk phosphorylates the adaptor protein SH2 domain-containing leukocyte protein of 65 kDa (SLP-65), thus coupling the BCR to diverse signalling pathways. Here, we report that SLP-65 is not only a downstream target and substrat...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2374840/ https://ncbi.nlm.nih.gov/pubmed/18369315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.62 |
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