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A Temporal Switch in the Germinal Center Determines Differential Output of Memory B and Plasma Cells

There is little insight into or agreement about the signals that control differentiation of memory B cells (MBC) and long-lived plasma cells (LLPC). By performing BrdU pulse-labeling studies, we found that MBC formation preceded the formation of LLPC in an adoptive transfer immunization system, whic...

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Bibliographic Details
Published in:Immunity
Main Authors: Weisel, Florian J, Zuccarino-Catania, Griselda, Chikina, Maria, Shlomchik, Mark J
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724390/
https://ncbi.nlm.nih.gov/pubmed/26795247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.12.004
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