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A Temporal Switch in the Germinal Center Determines Differential Output of Memory B and Plasma Cells
There is little insight into or agreement about the signals that control differentiation of memory B cells (MBC) and long-lived plasma cells (LLPC). By performing BrdU pulse-labeling studies, we found that MBC formation preceded the formation of LLPC in an adoptive transfer immunization system, whic...
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Publicado no: | Immunity |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4724390/ https://ncbi.nlm.nih.gov/pubmed/26795247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.12.004 |
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