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Fluorescence resonance energy transfer links membrane ferroportin, hephaestin but not ferroportin, amyloid precursor protein complex with iron efflux

Iron efflux from mammalian cells is supported by the synergistic actions of the ferrous iron efflux transporter, ferroportin (Fpn) and a multicopper ferroxidase, that is, hephaestin (Heph), ceruloplasmin (Cp) or both. The two proteins stabilize Fpn in the plasma membrane and catalyze extracellular F...

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Pubblicato in:J Biol Chem
Autori principali: Dlouhy, Adrienne C., Bailey, Danielle K., Steimle, Brittany L., Parker, Haley V., Kosman, Daniel J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422103/
https://ncbi.nlm.nih.gov/pubmed/30647129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005142
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