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Ferroportin and Exocytoplasmic Ferroxidase Activity Are Required for Brain Microvascular Endothelial Cell Iron Efflux

The mechanism(s) of iron flux across the brain microvasculature endothelial cells (BMVEC) of the blood-brain barrier remains unknown. Although both hephaestin (Hp) and the ferrous iron permease ferroportin (Fpn) have been identified in BMVEC, their roles in iron efflux have not been examined. Using...

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Detalhes bibliográficos
Main Authors: McCarthy, Ryan C., Kosman, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682590/
https://ncbi.nlm.nih.gov/pubmed/23640881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.455428
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