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Glial Cell Ceruloplasmin and Hepcidin Differentially Regulate Iron Efflux from Brain Microvascular Endothelial Cells

We have used an in vitro model system to probe the iron transport pathway across the brain microvascular endothelial cells (BMVEC) of the blood-brain barrier (BBB). This model consists of human BMVEC (hBMVEC) and C6 glioma cells (as an astrocytic cell line) grown in a transwell, a cell culture syste...

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Detalhes bibliográficos
Main Authors: McCarthy, Ryan C., Kosman, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923066/
https://ncbi.nlm.nih.gov/pubmed/24533165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089003
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