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Fluorescence resonance energy transfer links membrane ferroportin, hephaestin but not ferroportin, amyloid precursor protein complex with iron efflux

Iron efflux from mammalian cells is supported by the synergistic actions of the ferrous iron efflux transporter, ferroportin (Fpn) and a multicopper ferroxidase, that is, hephaestin (Heph), ceruloplasmin (Cp) or both. The two proteins stabilize Fpn in the plasma membrane and catalyze extracellular F...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Dlouhy, Adrienne C., Bailey, Danielle K., Steimle, Brittany L., Parker, Haley V., Kosman, Daniel J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422103/
https://ncbi.nlm.nih.gov/pubmed/30647129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005142
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