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Fluorescence resonance energy transfer links membrane ferroportin, hephaestin but not ferroportin, amyloid precursor protein complex with iron efflux

Iron efflux from mammalian cells is supported by the synergistic actions of the ferrous iron efflux transporter, ferroportin (Fpn) and a multicopper ferroxidase, that is, hephaestin (Heph), ceruloplasmin (Cp) or both. The two proteins stabilize Fpn in the plasma membrane and catalyze extracellular F...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Dlouhy, Adrienne C., Bailey, Danielle K., Steimle, Brittany L., Parker, Haley V., Kosman, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422103/
https://ncbi.nlm.nih.gov/pubmed/30647129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005142
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