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Is brain iron trafficking part of the physiology of the amyloid precursor protein?

The amyloid precursor protein is so named, because a proteolytic fragment of it was found associated with a neuropathic disorder now known as Alzheimer’s disease. This fragment, Aβ, along with tau makes up the plaques and tangles that are the hallmark of AD. Iron (and other first-row transition meta...

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Bibliografiska uppgifter
I publikationen:J Biol Inorg Chem
Huvudupphovsmän: Bailey, Danielle K., Kosman, Daniel J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8053252/
https://ncbi.nlm.nih.gov/pubmed/31578640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-019-01684-z
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