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Is brain iron trafficking part of the physiology of the amyloid precursor protein?
The amyloid precursor protein is so named, because a proteolytic fragment of it was found associated with a neuropathic disorder now known as Alzheimer’s disease. This fragment, Aβ, along with tau makes up the plaques and tangles that are the hallmark of AD. Iron (and other first-row transition meta...
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| Published in: | J Biol Inorg Chem |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8053252/ https://ncbi.nlm.nih.gov/pubmed/31578640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-019-01684-z |
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