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Fluorescence resonance energy transfer links membrane ferroportin, hephaestin but not ferroportin, amyloid precursor protein complex with iron efflux

Iron efflux from mammalian cells is supported by the synergistic actions of the ferrous iron efflux transporter, ferroportin (Fpn) and a multicopper ferroxidase, that is, hephaestin (Heph), ceruloplasmin (Cp) or both. The two proteins stabilize Fpn in the plasma membrane and catalyze extracellular F...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Dlouhy, Adrienne C., Bailey, Danielle K., Steimle, Brittany L., Parker, Haley V., Kosman, Daniel J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422103/
https://ncbi.nlm.nih.gov/pubmed/30647129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005142
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