The p12 subunit of human polymerase δ uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA)

Human DNA polymerase δ is essential for DNA replication and acts in conjunction with the processivity factor proliferating cell nuclear antigen (PCNA). In addition to its catalytic subunit (p125), pol δ comprises three regulatory subunits (p50, p68, and p12). PCNA interacts with all of these subunit...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Gonzalez-Magaña, Amaia, Ibáñez de Opakua, Alain, Romano-Moreno, Miguel, Murciano-Calles, Javier, Merino, Nekane, Luque, Irene, Rojas, Adriana L., Onesti, Silvia, Blanco, Francisco J., De Biasio, Alfredo
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2019
Sujets:
Protein Structure and Folding
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422072/
https://ncbi.nlm.nih.gov/pubmed/30655288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006391
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