The PCNA interaction motifs revisited: thinking outside the PIP-box

Proliferating cell nuclear antigen (PCNA) is a cellular hub in DNA metabolism and a potential drug target. Its binding partners carry a short linear motif (SLiM) known as the PCNA-interacting protein-box (PIP-box), but sequence-divergent motifs have been reported to bind to the same binding pocket....

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Detalhes bibliográficos
Publicado no:Cell Mol Life Sci
Main Authors: Prestel, Andreas, Wichmann, Nanna, Martins, Joao M., Marabini, Riccardo, Kassem, Noah, Broendum, Sebastian S., Otterlei, Marit, Nielsen, Olaf, Willemoës, Martin, Ploug, Michael, Boomsma, Wouter, Kragelund, Birthe B.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881253/
https://ncbi.nlm.nih.gov/pubmed/31134302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-019-03150-0
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