A novel non-canonical PIP-box mediates PARG interaction with PCNA

Poly(ADP-ribose) glycohydrolase (PARG) regulates cellular poly(ADP-ribose) (PAR) levels by rapidly cleaving glycosidic bonds between ADP-ribose units. PARG interacts with proliferating cell nuclear antigen (PCNA) and is strongly recruited to DNA damage sites in a PAR- and PCNA-dependent fashion. Her...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nucleic Acids Res
Prif Awduron: Kaufmann, Tanja, Grishkovskaya, Irina, Polyansky, Anton A., Kostrhon, Sebastian, Kukolj, Eva, Olek, Karin M., Herbert, Sebastien, Beltzung, Etienne, Mechtler, Karl, Peterbauer, Thomas, Gotzmann, Josef, Zhang, Lijuan, Hartl, Markus, Zagrovic, Bojan, Elsayad, Kareem, Djinovic-Carugo, Kristina, Slade, Dea
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2017
Pynciau:
Structural Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766153/
https://ncbi.nlm.nih.gov/pubmed/28934471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx604
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