DNA replication protein Cdc45 directly interacts with PCNA via its PIP box in Leishmania donovani and the Cdc45 PIP box is essential for cell survival

DNA replication protein Cdc45 is an integral part of the eukaryotic replicative helicase whose other components are the Mcm2-7 core, and GINS. We identified a PIP box motif in Leishmania donovani Cdc45. This motif is typically linked to interaction with the eukaryotic clamp proliferating cell nuclea...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Yadav, Aarti, Sharma, Varshni, Pal, Jyoti, Gulati, Pallavi, Goel, Manisha, Chandra, Udita, Bansal, Neha, Saha, Swati
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255605/
https://ncbi.nlm.nih.gov/pubmed/32413071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008190
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