Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers

Arraying antigens in a multivalent nanoparticle form is often employed in vaccine design, but in vivo mechanisms underlying the enhanced immunity elicited by such vaccines remain poorly understood. Here we studied the fate of two different heavily glycosylated HIV antigens in protein nanoparticle or...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Science
Main Authors: Tokatlian, Talar, Read, Benjamin J., Jones, Christopher A., Kulp, Daniel W., Menis, Sergey, Chang, Jason Y.H., Steichen, Jon M., Kumari, Sudha, Allen, Joel D., Dane, Eric L., Liguori, Alessia, Sangesland, Maya, Lingwood, Daniel, Crispin, Max, Schief, William R., Irvine, Darrell J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420719/
https://ncbi.nlm.nih.gov/pubmed/30573546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aat9120
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados