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Applications and limitations of fitting of the operational model to determine relative efficacies of agonists
Proper determination of agonist efficacy is essential in the assessment of agonist selectivity and signalling bias. Agonist efficacy is a relative term that is dependent on the system in which it is measured, especially being dependent on receptor expression level. The operational model (OM) of func...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6420642/ https://ncbi.nlm.nih.gov/pubmed/30874590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40993-w |
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