Pharmacokinetic-pharmacodynamic modelling to investigate in vitro synergy between colistin and fusidic acid against MDR Acinetobacter baumannii

OBJECTIVES: The potential for synergy between colistin and fusidic acid in the treatment of MDR Acinetobacter baumannii has recently been shown. The aim of this study was to perform an extensive in vitro characterization of this effect using pharmacokinetic-pharmacodynamic modelling (PKPD) of time–k...

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Détails bibliographiques
Publié dans:J Antimicrob Chemother
Auteurs principaux: Phee, Lynette M, Kloprogge, Frank, Morris, Rebecca, Barrett, John, Wareham, David W, Standing, Joseph F
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419616/
https://ncbi.nlm.nih.gov/pubmed/30624656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dky524
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