Pharmacokinetic-pharmacodynamic modelling to investigate in vitro synergy between colistin and fusidic acid against MDR Acinetobacter baumannii

OBJECTIVES: The potential for synergy between colistin and fusidic acid in the treatment of MDR Acinetobacter baumannii has recently been shown. The aim of this study was to perform an extensive in vitro characterization of this effect using pharmacokinetic-pharmacodynamic modelling (PKPD) of time–k...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Phee, Lynette M, Kloprogge, Frank, Morris, Rebecca, Barrett, John, Wareham, David W, Standing, Joseph F
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419616/
https://ncbi.nlm.nih.gov/pubmed/30624656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dky524
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