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Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death
Mutations of Fused in sarcoma (FUS), a ribonucleoprotein involved in RNA metabolism, have been found associated with both familial and sporadic cases of amyotrophic lateral sclerosis (ALS). Notably, besides mutations in the coding sequence, also mutations into the 3′ untranslated region, leading to...
Zapisane w:
| Wydane w: | Sci Rep |
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| Główni autorzy: | , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group UK
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6418113/ https://ncbi.nlm.nih.gov/pubmed/30872738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41040-4 |
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